ZakAria is a humanized monoclonal antibody directed against human cell surface receptor PD-1 (programmed death-1 or programmed cell death-1) with potential immune checkpoint inhibitory and antineoplastic activities.ZakAria® (Pembrolizumab) is used alone or in combination with other medicines to treat certain types of cancer including:
- Skin cancer (Melanoma and Merkel cell carcinoma)
- Lung cancer
- Head and neck cancer
- Certain types of lymphoma (Hodgkin and large B-cell)
- Cancer of the kidney, bladder, and urinary tract
- Colorectal cancer
- Liver cancer
- Breast cancer
- Cancer of the cervix or uterus
- Advanced stomach or esophageal cancer